Oral antidiabetic drugs Use with caution Glucose- lowering effect potentiated Hypoglycemia sometimes severe has been reported when ciprofloxacin and oral antidiabetic agents, mainly sulfonylureas for example, glyburide, glimepiride, were co- administered, presumably by intensifying the action of the oral antidiabetic agent.
doxycycline diarrhea Additionally, CTLA- 4- dependent inhibition of Akt, a downstream target of PP2A, is sensitive to the PP2A inhibitor okadaic acid, implying that PP2A plays an important role in CTLA- 4- mediated T cell inactivation 13.