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A protein that plays a key role in tumor formation, oxygen metabolism
converse chucks and inflammation is involved in a pathway that extends lifespan by dietary restriction. The finding,
new balance f眉r damen which appears in the May 22, 2009 edition of the on-line journal PLoS Genetics, provides a new understanding of how dietary restriction contributes to longevity and cancer prevention and gives scientists new targets for developing and testing drugs that could extend the healthy years of life.The protein is HIF-1 (hypoxia-inducible factor 1). It helps cells survive by turning on when oxygen levels are low. HIF-1 is also active in some forms of human cancer. HIF-1 overexpression is frequently detected in solid tumors; inhibition of HIF-1 has been proved to be an efficient way to prevent cancer growth.Now, scientists at the Buck Institute for Age Research have shown that HIF-1 is also a key player in dietary restriction. HIF-1 is involved in a molecular pathway known to regulate cell gr
dunk high nike owth and metabolism in response to DHARAMSALA:All-rounder Ravindra Jadeja starred with both bat and ball on the third day of the fourth Test on Monday to put India on course for a series-clinching victory against Australia in Dharamsala.The left-hander top-scored with 63 to help India surpass Australia's first innings total of 300 and then snared three wickets with his spin bowling to dim the visitors' hopes of victory.India's pacemen did the early damage. Umesh Yadav picked up two wickets and Bhuvneshwar Kumar dismissed the in-form Australian skipper Steve Smith for 17 to leave the Aussies reeling on 31-3 inside 10 overs.Dream debut for Kuldeep overshadows Smith鈥檚 record tonA short ball hit the bottom edge of Smith's bat before crashing onto the stumps in spectacular fashion.Smith amassed 499 runs including three centuries from the four Tests, only the sixth visiting batsman to score so many hundre
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new balance homme n a lively track that offered plenty of pace and bounce, w
