Modafinil et adrafinil >>>
Adrafinil. Adrafinil is a unique smart drug for a few reasons. First, the nootropic is 100% legal to buy over-the-counter, though you cannot buy it on Amazon. Plus, Adrafinil offers Modafinil-like effects, as the smart drug converts to Modafinil once inside the body . While this certainly offers impressive cognitive benefits, Adrafinil effects ...
Modafinil appeared to be more potent than adrafinil in animal studies, and was selected for further clinical development, with both adrafinil and modafinil eventually reaching the market. Modafinil was first approved in France in 1994, and then in the United States in 1998. Lafon was acquired by Cephalon in 2001.
Jean-Pierre P, Morrow GR, Roscoe JA, et al. A phase 3 randomized, placebo-controlled, double-blind, clinical trial of the effect of modafinil on cancer-related fatigue among 631 patients receiving chemotherapy: a University of Rochester Cancer Center Community Clinical Oncology Program Research base study.
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Modafinil is the primary metabolite of adrafinil, lacking the polar -OH group on its terminal amide, and has similar activity to the parent drug but is much more widely used. It has been prescribed in France since 1994 under the name Modiodal, and in the US since 1998 as Provigil.
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↑ Oberle D et al. Incidence of Narcolepsy in Germany, Sleep, Volume 38, Issue 10, 1 October 2015, Pages 1619–1628, abgerufen am 05.08.2020 ↑ Johns MW A new method for measuring daytime sleepiness: the Epworth sleepiness scale , Sleep. 1991 Dec;14(6):540-5, abgerufen am 05.08.2020
