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These problems may be due to the tumour or made worse by surgery chemotherapy and medicines such as dexamethasone, morphine-like medicine and anticonvulsant medicines. In 1946, Molnar, in his classical paper, emphasized the relationship between survival times and water temperatures below fifty nine F (15 C). It may seem in states of fatigue or persistent ache, or be a medical function of temperamental anomalies related to advancing age, cerebral trauma, epileptic states, and manic-depressive issues
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